Evaluation of the Antiplasmodial Properties of <i>Andrographis paniculata</i> (Burm.f.) and <i>Peperomia pellucida</i> (L.) Kunth

Plasmodium species are the infectious agents that responsible for malaria, a disease claims lives of approximately 400,000 people annually. The fact drug resistance against malaria is on rise suggests new antimalarial compounds need to be discovered. It well known medicinal plants present best opportunity identification novel antimalaria chemicals. Both Andrographis paniculata (Burm.f.) and Peperomia pellucida (L. Kunth) have been tested their antiplasmodial ability falciparum strain. P. has also subjected in vitro vivo biological research. was used isolate steroid as 3-hydroxy-24-ethyl-5,22-cholestadiene (1) triterpenoid 3-hydroxy-9-lanosta-7,24E-dien-26-oic acid (2). were then activity vitro. In mice model, 2 had substantial chemo-suppressive impact.